Determination of the activity of ponazuril against Sarcocystis neurona in cell cultures.
نویسندگان
چکیده
The present study examined the efficacy of ponazuril in inhibiting merozoite production of Sarcocystis neurona in cell cultures. Ponazuril inhibited merozoite production by more that 90% in cultures of S. neurona treated with 1.0 microg/ml ponazuril and greater than 95% inhibition of merozoite production was observed when infected cultures were treated with 5.0 microg/ml ponazuril. Ponazuril may have promise as a therapeutic agent in the treatment of S. neurona induced equine protozoal myeloencephalitis (EPM) in horses.
منابع مشابه
Determination of the activity of diclazuril against Sarcocystis neurona and Sarcocystis falcatula in cell cultures.
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ورودعنوان ژورنال:
- Veterinary parasitology
دوره 92 2 شماره
صفحات -
تاریخ انتشار 2000